You’ve read the research. You know your 40s are the critical window for bone density. You want to take action.
Here’s exactly what to do.
Step 1: Get a Baseline DEXA Scan
Before you do anything else, know where you stand. A DEXA scan takes about 10 minutes, is non-invasive, and gives you a T-score that tells you your bone density relative to peak bone mass.
Supplement Recommendation
I order everything through The Village Library’s Fullscript dispensary — professional-grade, up to 20% off retail. Same brands used by integrative physicians.
Ask your doctor to order one. If they won’t, you can often self-pay at radiology centers for $50-150.
Prenuvo’s comprehensive body scan includes bone density assessment — worth considering if you want a complete picture of your health at the same time.
Step 2: Start Resistance Training
No supplement replaces mechanical load. Compound movements — squats, deadlifts, hip hinges, rows, overhead presses — signal your body to build and maintain bone.
If you’re new to lifting, start with a trainer or a structured beginner program. The investment pays for itself.
Starting Strength on Amazon → — the gold standard beginner strength training book
The New Rules of Lifting for Women on Amazon → — specifically designed for women
Step 3: Build the Supplement Stack
Vitamin D3 + K2 — get your level tested first. Target 50-80 ng/mL. Most people need 2,000-5,000 IU/day to achieve this.
Vitamin D3 + K2 on Amazon →
Magnesium Glycinate — required for calcium metabolism and bone formation. 300-400mg before bed.
Magnesium Glycinate on Amazon →
Creatine Monohydrate — 3-5g/day. Stanford research shows creatine + resistance training increases bone mineral density in women. Also preserves muscle and supports cognitive function.
Creatine Monohydrate on Amazon →
HMB — 3g/day. Reduces muscle protein breakdown. Preserves lean mass during menopause. Particularly valuable if you’re on a GLP-1 or can’t yet train at high intensity.
HMB on Amazon →
Collagen Peptides — Type I collagen for bone matrix support. Take with Vitamin C.
Collagen Peptides on Amazon →
For professional-grade versions of all of the above: Fullscript offers practitioner-quality supplements at a discount — the same brands integrative physicians use.
Step 4: What to Ask Your Doctor
- Can you order a DEXA scan? What’s my T-score?
- What is my Vitamin D level? (Request 25-OH Vitamin D test)
- Am I a candidate for HRT? (Estrogen is the most powerful bone-protective intervention available for perimenopausal women)
- Do I have any other risk factors for osteoporosis I should know about?
Step 5: Track Your Progress
Retest your DEXA scan every 1-2 years to see if your intervention is working. Track your strength progress in the gym — getting stronger is a proxy for bone adaptation. The Oura Ring tracks recovery and HRV — useful for ensuring your training isn’t outpacing your recovery.
Shop Oura Ring 4 → (affiliate)
Related reading:
- The Bone Density Crisis Nobody Talks About Until It’s Too Late
- The Supplement Conversation Every Woman in Her 40s Should Be Having
- GLP-1s: What Every Woman Should Know (if you’re on a GLP-1, bone health is especially critical)
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The information in this post is for educational purposes only and does not constitute medical advice. Please consult a qualified physician for guidance specific to your situation. Some links are affiliate links — see our full Affiliate Disclosure.

